What is the difference between allografts and autografts?

The distinction between allografts and autografts is rooted in the source of the tissue being transplanted. Allografts are defined as tissues that are transplanted from one individual to another, typically from a deceased or unrelated living donor. This is essential in various surgical procedures where the recipient's tissue cannot be used due to damage or deficiency.

In contrast, autografts involve tissue taken from the same individual who will receive the transplant. This type of graft minimizes the risk of rejection because the tissue is recognized by the immune system as 'self,' allowing for a high rate of compatibility and integration.

This understanding is crucial in clinical practice and in the management of transplant recipients, as autografts are generally preferred when possible due to their lower likelihood of rejection and complications compared to allografts.